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Sandostatin: Each Sandostatin ampoule also contains lactic acid, mannitol, sodium hydrogen carbonate and water for injection.
Sandostatin LAR: Powder: White to white with yellowish tint powder.
Solvent for suspension for injection: Clear, colorless to slightly yellow or brown solution.
Sandostatin LAR is a long-acting depot injection form of octreotide. Powder (microspheres for suspension for injection) to be suspended in a vehicle immediately prior to i.m. injection.
The active substance is octreotide free peptide. 20 mg or 30 mg nominally 4.15% of fill weight equivalent to 4.65% of octreotide acetate.
Excipients/Inactive Ingredients: Sandostatin LAR: Vial: Poly(DL-lactide-co-glycolide) 78.35% of nominal fill weight; sterile mannitol 17.0% of nominal fill weight.
Prefilled syringe: Kit with vial adapter and safety needle: One prefilled syringe (solvent for parenteral use), containing: sodium carboxymethylcellulose (14 mg), mannitol (12 mg), poloxamer 188 (4 mg); water for injection qs ad 2 mL.
